The last F-117s scheduled to fly will leave Holloman [Air Force Base in New Mexico] on April 21, stop in Palmdale, California, for another retirement ceremony, then arrive on April 22 at their final destination: Tonopah Test Range Airfield in Nevada, where the jet made its first flight in 1981.

Updated

Lift-off for Endeavour.

Mission summary from the Wikipedia article:

It will be the twenty-fifth shuttle mission to visit the ISS, and will deliver the first module of the Japanese laboratory, Japanese Experiment Module (Kibō), and the Canadian Special Purpose Dexterous Manipulator, (SPDM) Dextre robotics system to the station. The current mission duration is set for sixteen days, but given this will be the first mission fully utilizing the SSPTS, which uses space station power to augment the shuttle power systems, and with extension days built in, this mission has the ability to be the longest shuttle flight in history.

Going to be a busy year for the ageing STS.

Spaceflight Now links:

• Launch story
• Mission Status Center

Looks like there were a couple minor issues on ascent:

• The flash evaporator cooling system (via The Write Stuff) switched to its backup controller. Apparently this has happened on previous flights with the only impact being a reduction in redundancy in the system. The evaporators are used to cool the orbiter systems during ascent and re-entry i.e. when the payload bay radiators are not available.
• A card has failed in an electronics box that controls instrumentation for a number of thrusters on the left hand side of the shuttle. Other thrusters will be used instead.
• A piece of debris was seen 83 seconds into the ascent but missed the port wing. No doubt the now usual detailed examination of the heat shield will look for any other issues.

Related to the debris, this mission featured a “new Nikon flash system to illuminate the tank. The goal was to collect detailed digital pictures to help engineers assess the condition of the tank’s foam insulation even in orbital darkness.” Link to description in the press kit (see page 77 - hyperlink doesn’t seem to work).

According to the flight day two execute package: The new flash units were dramatic and effective.

Link to video showing separation from a camera on the External Tank. For a few seconds near the end it shows the flash going off. I was really surprised how much light the thrusters give off.

Links from the NASA website:

• Execute Packages - updates from mission control to the Space Shuttle crew. Always fasinating.
• Press Kit